a multicenter, observational study of 10,000 older women.
SOF, a nationwide research study funded by the
National Institutes of Health,
began in 1986. The study was originally focused on risk factors for fractures and
falls and has grown to look at various determinants of successful aging.
SOF Online provides access to the SOF data and documentation.
Baseline questionnaire and exam data for original (Caucasian) cohort (N=9,704)
Visit 2 (Year 2) questionnaire and exam data for original (Caucasian) cohort
Visit 3 (Year 4) questionnaire and exam data for original (Caucasian) cohort
Visit 4 (Year 6) questionnaire and exam data for original (Caucasian) cohort
Visit 5 (Year 8) questionnaire and exam data for original (Caucasian) cohort
Visit 6 (Year 10) questionnaire and exam data for original (Caucasian) cohort and Baseline questionnaire and exam data for African American cohort (N=662)
Visit 7 (Year 12) questionnaire and exam data for AA cohort (Visit 2) and subset of Caucasian cohort
Visit 8 (Year 16) questionnaire and exam data for entire cohort
Visit 9 (Year 20) questionnaire and exam data for entire cohort (additional sleep measures in subset)
Outcomes: fractures, breast cancer and mortality
Lab Data: Data from multiple assays available in following substudies: Fracture Death Case Cohort, Breast Cancer Case Cohort, and Stroke Case Cohort (See "Data Availability for Public Data Release" in "Data & Documentation" for details)
Visit 2 (Year 2) serum, blood blotters and DNA for original cohort and urine in a subset
Visit 4 (Year 6) serum and urine on original cohort
Visit 6 (Year 10) serum and urine on entire cohort
Visit 7 (Year 12) serum and blood blotters in AA cohort
Visit 8 (Year 16) blood blotters, whole blood and DNA on entire cohort
SOF Online is designed to work best with Internet Explorer 8+
or FireFox 4+,
and Adobe Acrobat 10+. All are freely available.
SOF Online is intended as a means to learn about and retrieve the data collected in the Study of Osteoporotic Fractures. By using SOF Online, users imply understanding of these intended uses and agree not to use the website or downloadable materials for any other purpose.
Create an account now!
You must have an account and accept the terms of a Data Use Agreement before you can download or explore clinical data.
Please go to My Account and create a new account now.
Tutorial: Where do I begin? Try the SOF Online Tutorial
which walks you through the variety of tools available on SOF Online for touring and understanding the data.
Search/browse:Search/browse a database of categorized variable documentation
displayed longitudinally with links to statistics, comments, and annotated data collection forms.
My Cart: Create a personal cart of variables of interest that
can be used 1) to build a custom codebook able to be
read offline, and 2) to filter downloadable datasets.
DataExplorer: Use DataExplorer
to generate descriptive statistics: cross tabs, subsets, frequency distributions and more. Note this tool requires an account and acceptance of the terms of a Data Use Agreement.